- Pick the high hanging fruit -
Specimen improvement for structural analysis
by (cryo-) EM and X-ray crystallography
with ProteoPlex MacroDSF
ProteoPlex MacroDSF technology can
greatly improve sample quality for structural
studies of proteins by (cryo-) EM
and X-ray crystallography.
We believe that structural biology
will shift more and more towards
The Protein Data Bank (PDB) currently
holds 148,000 protein entries, but
only 1% are multi-domain proteins
- because they are difficult to do.
A multitude of structural studies have
been performed on individual proteins.
But most proteins form a network of
interactions with other proteins and many
are components of large complexes in-vivo.
The understanding of this protein complex
formation and function is still very limited,
because most protein complexes pose high
challenges in terms of preparation and handling.
Obtaining high-quality structural information
of complexes therefore requires new,
sophisticated methods and know-how;
things that ProteoPlex can offer.
This enables scientists to create an optimized,
robust, high-yield pipeline for the purification
and crystallization of proteins.
ProteoPlex MacroDSF helps you
grab the high hanging fruit by
boosting your sample quality,
ensuring that your research
stays ahead of the curve.
All ProteoPlex technologies are exclusively licensed from
Joint press release with NovAliX, 27th March 2018
Press release MPG,
7th Nov 2017:
Press release EMBL,
4th Aug 2016:
8th Aug 2016: