- Pick the high hanging fruit -

 

Specimen improvement for structural analysis

by (cryo-) EM and X-ray crystallography

with ProteoPlex MacroDSF

 

ProteoPlex MacroDSF technology can

greatly improve sample quality for structural

studies of proteins by (cryo-) EM

and X-ray crystallography.

 

We believe that structural biology

will shift more and more towards

challenging structures.

 

The Protein Data Bank (PDB) currently

holds almost 142,000 protein entries, but

only 1% are multi-domain proteins

- because they are difficult to do.

 

A multitude of structural studies have

been performed on individual proteins.

But most proteins form a network of

interactions with other proteins and many

are components of large complexes in-vivo.

 

The understanding of this protein complex

formation and function is still very limited,

because most protein complexes pose high

challenges in terms of preparation and handling.

 

Obtaining high-quality structural information

of complexes therefore requires new,

sophisticated methods and know-how;

things that ProteoPlex can offer.

 

This enables scientists to create an optimized,

robust, high-yield pipeline for the purification

and crystallization of proteins.

 

ProteoPlex MacroDSF helps you

grab the high hanging fruit by

boosting your sample quality,

ensuring that your research

stays ahead of the curve.

____________________________________________

All ProteoPlex technologies are exclusively licensed from

Joint press release with NovAliX, 27th March 2018

"NovAliX enters into cooperation agreement with ProteoPlex"

Press release EMBL,

4th Aug 2016:

"Every atom counts"

EMBL Science,

8th Aug 2016:

"Blocking the cell's waste disposal unit"